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	This site best viewed at a resolution of at least 1024x768 and a 32 bit color depth.   Welcome to CLM Latest CLM/PML Lab Update Cardiac Troponins Troponins of cardiac origin are regulatory proteins that control the calcium mediated interaction of Actin and Myosin. The troponin complex consists of three subunits: Troponin T, which binds to Tropomyosin and facilitates contractions; Troponin I, which binds to Actin and inhibits Actin/Myosin interaction; and Troponin C, which binds the calcium ions . The amino acid sequence of the skeletal and cardiac isoforms of Troponin T and Troponin I are sufficiently dissimilar and therefore detectable by monoclonal antibody assay. Troponin C is not used clinically because both…  More...   The mission of Consultants in Laboratory Medicine of Greater Toledo is to be the provider of choice in anatomic pathology and laboratory medicine consultative services becoming an essential part of the medical team. We desire to positively impact the delivery of healthcare in the community by providing leading edge, highly relevant and personalized laboratory medicine. These related services are knit tightly with front line physician practice, through application of expert knowledge and information technologies to address present and emerging needs. We provide diagnostic and consultative services with unrelenting passion to provide unsurpassed quality as a valued member of the care giving team.	Medscape Pathology News Fri, 16 May 2008 16:04:15 EDT Serum Phosphate Linked to Mortality Among CKD Patients Not on Dialysis Fri, 16 May 2008 07:04:22 EDT Serum phosphate levels within the high-normal range could be an independent predictor of mortality among people with chronic kidney disease, even those not on dialysis. Medscape Medical News   FAST Trial Published: No Benefit of Factor VII in Treatment of ICH Fri, 16 May 2008 12:37:20 EDT Disappointing phase 3 results failed to confirm promising phase 2b findings, showing that although recombinant activated factor VII reduced hematoma growth in patients with acute intracerebral hemorrhage, it did not improve survival or functional outcome. Medscape Medical News   "Delipidated" HDL: A New, Autologous Option for Plaque Regression? Fri, 16 May 2008 14:46:10 EDT Very preliminary data from a pilot study indicates that stripping a patient's own HDL of its lipid content, then reinfusing it, is feasible and safe and may even offer a novel means of stabilizing atherosclerotic plaques. Heartwire   Guidelines Issued on Pertussis, Tetanus, Diphtheria Prevention in Pregnant Women and Newborns Fri, 16 May 2008 17:00:00 EDT The Advisory Committee on Immunization Practices has issued guidelines on the prevention of pertussis, tetanus, and diphtheria in pregnant and postpartum women and their infants. Medscape Medical News   Risk for Urologic Cancer Linked to Risk for Colorectal Cancer Fri, 16 May 2008 17:00:00 EDT Patients with renal pelvis and ureteral cancers have an increased risk for colorectal cancer, and in turn, a history of colorectal cancer increases the risk for renal pelvis and ureteral cancers. Medscape Medical News
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